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5-Amino-1MQ

Animal / preclinical
Metabolic / fat-lossMetabolic / fat loss (claimed)

Community-reported ranges are anecdotal and not clinically validated. Evidence grade shown reflects the strength of available human data. Not a prescription. Legal status varies by country and changes over time; verify locally.

Overview

A small-molecule NNMT inhibitor (not strictly a peptide) from academic obesity research, where it shrank fat cells and reduced weight in diet-induced obese mice without appetite suppression. Oral and popular in metabolic stacks; human trials haven't started.

Mechanism

Inhibits nicotinamide N-methyltransferase (NNMT), raising NAD+ availability in fat tissue and shifting adipocyte metabolism in animal studies.

Evidence

Animal / preclinicalWhat does this mean?

Compelling rodent fat-loss data via a novel mechanism; human efficacy and safety are untested.

Community-reported information

Community reports vary. Anecdotal and unvalidated; general information only.

General information only, not tailored to you and not a recommendation. Some regions withhold this entirely.

Half-life

Not well characterised in humans (oral use common).

Storage

Room temperature (capsule formulations).

Commonly reported side effects

  • Not well characterised in humans

Legal status by region

  • USNot FDA-approved; not a lawful supplement ingredient.

Legal status changes over time; verify locally before relying on this.