Longevity

Peptides studied for anti-ageing and mitochondrial health — some of the most scientifically interesting molecules in the library, with evidence ranging from human association studies to single-group clinical programmes awaiting replication.

Community-reported ranges are anecdotal and not clinically validated. Evidence grade shown reflects the strength of available human data. Not a prescription. Legal status varies by country and changes over time; verify locally.

4 peptides

Epithalon

Anecdote / community

Epitalon, AEDG

A synthetic tetrapeptide from the long-running Russian bioregulator programme, where decades of studies reported telomerase activation and improved survival in elderly cohorts. Those results are intriguing but come largely from one research group, without independent replication yet.

SS-31 (Elamipretide)

Human observational

Elamipretide, MTP-131

A mitochondria-targeting peptide in clinical development for mitochondrial and cardiac disease. Investigational; not approved.

Humanin

Animal / preclinical

HN, Mitochondrial-derived peptide

The first mitochondrial-derived peptide discovered, studied for protecting cells against stress-induced death, with human studies linking higher natural levels to longevity — centenarian families show elevated humanin. Supplementation itself hasn't been trialled.

Glutathione

Human observational

GSH, L-glutathione

The body's main intracellular antioxidant, a tripeptide of glutamate, cysteine and glycine. It has legitimate research and some clinical uses, but injectable use for skin-lightening is unproven and has drawn safety warnings from regulators.