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GHK-Cu

Human observational

Also known as: Copper peptide, Glycyl-L-histidyl-L-lysine copper

CosmeticSkin / cosmetic (topical)Hair (claimed)

Community-reported ranges are anecdotal and not clinically validated. Evidence grade shown reflects the strength of available human data. Not a prescription. Legal status varies by country and changes over time; verify locally.

Overview

A naturally occurring copper-binding tripeptide widely used in topical cosmetics, where it has the most support. Injectable use is anecdotal.

Mechanism

Binds copper and is studied for effects on collagen, wound signalling and skin remodelling, mostly in vitro and topically.

Evidence

Human observationalWhat does this mean?

Moderate for topical cosmetic use; weak for injected/systemic claims.

Community-reported information

Topical products list their own concentrations. Injected community use is anecdotal and unvalidated.

General information only, not tailored to you and not a recommendation. Some regions withhold this entirely.

Half-life

Short.

Storage

Store cool and dark; reconstituted solutions refrigerated.

Commonly reported side effects

  • Skin irritation (topical)
  • Injection-site reactions reported anecdotally

Legal status by region

  • USUsed in cosmetics; injectable use not FDA-approved.
  • GBCosmetic topical use common; injectable human use not licensed.

Legal status changes over time; verify locally before relying on this.

Citations