PT-141 (Bremelanotide)
Human RCTApproved medicineAlso known as: Vyleesi, Bremelanotide
Community-reported ranges are anecdotal and not clinically validated. Evidence grade shown reflects the strength of available human data. Not a prescription. Legal status varies by country and changes over time; verify locally.
Overview
A melanocortin-receptor agonist approved as bremelanotide (Vyleesi) for premenopausal women with HSDD. Other uses are off-label.
Mechanism
Activates melanocortin receptors in the central nervous system influencing sexual response.
Evidence
Strong within its approved indication; off-label use is not supported by that approval.
Community-reported information
Prescription medicine dosed per label and clinician within its indication.
General information only, not tailored to you and not a recommendation. Some regions withhold this entirely.
Half-life
~2.7 hours.
Storage
Room temperature per label.
Commonly reported side effects
- Nausea
- Flushing
- Headache
- Injection-site reactions
Legal status by region
- USFDA-approved (Vyleesi) for a specific indication; prescription only.
Legal status changes over time; verify locally before relying on this.