Ipamorelin
Animal / preclinicalWADA prohibitedCommunity-reported ranges are anecdotal and not clinically validated. Evidence grade shown reflects the strength of available human data. Not a prescription. Legal status varies by country and changes over time; verify locally.
Overview
A selective growth-hormone secretagogue (ghrelin-receptor agonist) popular in longevity circles. Human efficacy for the claimed physique/recovery benefits is unproven.
Mechanism
Stimulates pituitary growth-hormone release via the ghrelin receptor with relatively little effect on cortisol/prolactin.
Evidence
Thin for the marketed physique/anti-ageing claims; mechanistic and preclinical support only.
Community-reported information
Community reports vary. Anecdotal and unvalidated; general information only.
General information only, not tailored to you and not a recommendation. Some regions withhold this entirely.
Half-life
~2 hours.
Storage
Lyophilised: refrigerate. Reconstituted: refrigerate, use within weeks.
Commonly reported side effects
- Head-rush
- Water retention
- Injection-site reactions
Legal status by region
- USNot FDA-approved; removed from compounding permissibility lists.
- AUPrescription-only; import controlled.
Legal status changes over time; verify locally before relying on this.