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Category

Growth-hormone secretagogues

Growth-hormone secretagogues and releasing peptides. Most are WADA-prohibited and their marketed physique benefits are thinly evidenced in humans.

Community-reported ranges are anecdotal and not clinically validated. Evidence grade shown reflects the strength of available human data. Not a prescription. Legal status varies by country and changes over time; verify locally.

11 peptides

Ipamorelin

Animal / preclinical

A selective growth-hormone secretagogue (ghrelin-receptor agonist) popular in longevity circles. Human efficacy for the claimed physique/recovery benefits is unproven.

WADA prohibited

CJC-1295

Animal / preclinical

with DAC, Mod GRF (1-29)

A growth-hormone-releasing-hormone analogue often paired with ipamorelin. Human evidence for the marketed benefits is limited.

WADA prohibited

Sermorelin

Human observational

GHRH (1-29)

A GHRH analogue previously used diagnostically for GH deficiency. Marketed today for anti-ageing with weaker support for those uses.

WADA prohibited

Tesamorelin

Human RCT

Egrifta

A GHRH analogue approved to reduce excess abdominal fat in HIV-associated lipodystrophy. Off-label physique use is not supported by that approval.

Approved medicineWADA prohibited

MK-677 (Ibutamoren)

Human observational

Ibutamoren

An orally active ghrelin-receptor agonist that raises GH and IGF-1. Investigated in trials but not approved; popular for physique use.

WADA prohibited

Hexarelin

Animal / preclinical

A potent growth-hormone-releasing peptide (GHRP). Popular for physique goals; human efficacy for those claims is unproven and tolerance can develop.

WADA prohibited

GHRP-6

Animal / preclinical

Growth Hormone Releasing Peptide-6

An early growth-hormone-releasing peptide known for a strong hunger response. Human efficacy for physique goals is unproven.

WADA prohibited

GHRP-2

Human observational

Pralmorelin

A growth-hormone-releasing peptide used in some countries as a diagnostic agent (pralmorelin). Physique-use claims are weakly supported.

WADA prohibited

IGF-1 LR3

Animal / preclinical

Long R3 IGF-1

A modified, long-acting form of insulin-like growth factor 1 used in bodybuilding. Carries real risks (hypoglycaemia, tissue growth) and is WADA-prohibited.

WADA prohibited

PEG-MGF

Animal / preclinical

Mechano Growth Factor, IGF-1Ec, Pegylated MGF

A pegylated form of mechano growth factor, a splice variant of IGF-1 expressed in muscle after mechanical stress. Marketed for muscle repair; human evidence for the marketed claims is absent and it is WADA-prohibited.

WADA prohibited

Follistatin-344

Animal / preclinical

FS-344

A form of follistatin, a natural protein that binds and inhibits myostatin. Studied mainly in gene-therapy and animal models for muscle growth; injectable-product claims are unproven and it falls under WADA's myostatin-related prohibitions.

WADA prohibited